LONGEVITY

Calibrate

Microdose Tirzepatide Injectable

from $179 / month

Calibrate is a clinician-guided microdose tirzepatide program for gradual, sustainable metabolic optimization.

Using lower, carefully managed doses of tirzepatide, Calibrate is designed for those seeking a measured entry into metabolic support, with the same clinician oversight and pharmacy standards as our full programs.

Tirzepatide activates the GIP and GLP-1 receptor pathways involved in appetite and metabolism. Calibrate uses lower, carefully titrated doses intended for a gentler, more gradual approach. Your clinician determines whether a microdose protocol suits your goals and adjusts it over time.

A measured, lower-dose approach to metabolic support
Dual GIP and GLP-1 pathway engagement
Supports appetite awareness and gradual progress
Clinician-guided titration throughout
Same pharmacy and testing standards as our full programs

Nausea, particularly early in the program
Constipation or diarrhea
Mild fatigue or headache
Temporary injection site redness or discomfort

Personal or family history of medullary thyroid carcinoma or MEN 2
Pregnancy or breastfeeding
History of pancreatitis
Known hypersensitivity to tirzepatide or any formulation component

A clinician reviews your intake first. If clinically appropriate, they may prescribe medication. Not all intakes are guaranteed to result in a filled prescription. You are not charged unless a clinician issues a prescription issued and filled. Actual vial appearance, contents, and dosage may vary based on your individual prescription as determined by your clinician. Compounded medications are not reviewed by the FDA for safety, effectiveness, or quality. Individual results vary.